Lesson
Use time to investigate an acquisition anomaly
Investigate a transient event-rate change without automatically deleting inconvenient events or mistaking event order for measured time.
Open learning item →CFCM Academy / Curriculum edition
Understand the signal.
Strengthen the interpretation.
A structured learning framework for clinical flow cytometry, from instrument physics and laboratory quality to disease-specific analysis.
Explore seven modulesBrowse by diseaseExplore all 95 topics
Find a topic by keyword, module or disease and open its curriculum outline.
Search the curriculumThe curriculum is open to explore
Explore module outlines and learning pathways, then work through the first seven editorially approved lessons below. Each lesson includes a worked example, questions and source references. More lessons and cases are in development.
Our publishing sequence is simple: learn → verify → synthesise → publish. Each teaching item needs traceable sources and accountable editorial review before release. Independent scientific review will be identified only where it has actually occurred.
Seven modules. One connected practice.
Start with the foundations or enter through a practical question. MRD is studied within each relevant disease pathway.
Module 01
Understanding the Physics of Flow Cytometry
Explore the instrument from sample stream to measured signal, with a learning sequence covering light, fluorescence and measurement quality.
Explore the curriculum →Module 02Cytometry Laboratory GMP & Quality
Follow the laboratory workflow through quality control, documentation and traceability. Topics distinguish general quality practice from requirements that depend on the laboratory's intended activities.
Explore the curriculum →Module 03Panel Design Insights
Build a structured approach to selecting markers and fluorochromes, then review controls and the evidence needed to assess a panel.
Explore the curriculum →Module 04Cytometer & Panel Setup
Connect instrument setup with panel optimisation and long-term monitoring. The curriculum separates transferable principles from instrument-specific instructions.
Explore the curriculum →Module 05Troubleshooting & Problem Solving
Work through problems by identifying the affected stage, checking evidence and documenting the investigation before changing a workflow.
Explore the curriculum →Module 06Validation & Verification
Organise a study around intended use, performance claims and the questions that its data must answer. The topics connect study design, analysis and reporting.
Explore the curriculum →Module 07Data Analysis of Haematological Malignancies
Learn through disease-centred pathways that connect diagnostic interpretation, follow-up and case discussion. MRD is studied within the relevant disease pathway.
Explore the curriculum →Within data analysis
Find your disease pathway
Diagnostic interpretation, follow-up and MRD are organised in their clinical context.
Disease pathway
B-cell Acute Lymphoblastic Leukaemia (B-ALL)
A disease-centred learning pathway for B-cell Acute Lymphoblastic Leukaemia (B-ALL). Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayT-cell Acute Lymphoblastic Leukaemia (T-ALL)
A disease-centred learning pathway for T-cell Acute Lymphoblastic Leukaemia (T-ALL). Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayAcute Myeloid Leukaemia (AML)
A disease-centred learning pathway for Acute Myeloid Leukaemia (AML). Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayChronic Lymphocytic Leukaemia (CLL)
A disease-centred learning pathway for Chronic Lymphocytic Leukaemia (CLL). Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayB-cell lymphoproliferative disorders (B-LPD)
A disease-centred learning pathway for B-cell lymphoproliferative disorders (B-LPD). Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayPlasma cell neoplasms
A disease-centred learning pathway for Plasma cell neoplasms. Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Disease pathwayMyelodysplastic neoplasms / MDS
A disease-centred learning pathway for Myelodysplastic neoplasms / MDS. Explore diagnostic interpretation, follow-up, reporting and case discussion within the same clinical context.
Explore the curriculum →Choose a learning path
Suggested learning sequences connect the curriculum. The first seven lessons are available below; progress tracking is not active.
Learning path
Clinical Flow Cytometry Foundations
Start with instrument principles, laboratory quality and basic panel design.
Explore the curriculum →Learning pathPanel Design
Follow marker and fluorochrome selection through controls, setup and panel assessment.
Explore the curriculum →Learning pathValidation & Verification
Work from intended use and performance claims to study design, analysis and reporting.
Explore the curriculum →Learning pathDisease-specific MRD
Study MRD within the appropriate disease pathway, with links to detection, quantification and reporting.
Explore the curriculum →Latest released learning
Lessons, cases and resources appear only after their stated editorial checks are complete. Independent scientific review is identified separately when it has actually occurred.
Cases & challenges
Released cases will connect observations, interpretation, differential diagnoses and the limits of the evidence. Questions will appear before the explanation.
No Academy cases have been released yet. Patient-identifiable material will not be used.
Read existing Clinical Notes →Learning levels
Foundation → Intermediate
Build the concepts, then connect them to practical laboratory decisions.
Advanced → Expert case
Examine complex interpretation, validation decisions and uncertainty.
Search the curriculum or choose one of the released lessons. Lesson-level filters and progress tracking are not available.